2,5-Dibromopyridine → 5-Bromo-2-(tetrahydro-2H-pyran-4-yloxy)pyridine

HRID 1245810Notes

Reaction equation

HRID 1245810 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[O:9]1[CH2:14][CH2:13][CH:12]([OH:15])[CH2:11][CH2:10]1>>[O:9]1[CH2:14][CH2:13][CH:12]([O:15][C:2]2[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 693532,5-DibromopyridineHCID 74956Tetrahydro-4H-pyran-4-ol

Product 1

HCID 219143915-Bromo-2-(tetrahydro-2H-pyran-4-yloxy)pyridine

Procedure

Prepared from 2,5-dibromopyridine and tetrahydropyran-4-ol by the method of Example 10 (b).

Sources & evidence

ORD record
ord-0f2c3b6a49274e50840250b1ec90e004
Source dataset
uspto-grants-2006_10
Patent number
US07125896B2

Reaction notes

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