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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246094Generated: October 27, 2026

6-Phenyl-1,3-dihydro-indol-2-one → 3-Methyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid (3-diethylaminopropyl)amide

https://huagongshe.com/reaction/1246094

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Phenyl-1,3-dihydro-indol-2-oneHCID 10536384—
Reactant5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylaminopropyl) amideHCID 86586196—
Product3-Methyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid (3-diethylaminopropyl)amideHCID 67281127—

Reaction Steps

6-Phenyl-1,3-dihydroindol-2-one (105 mg, 0.5 mmol) was condensed with 5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylaminopropyl)amide to give 67.8 (30%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125905B2
Source datasetuspto-grants-2006_10
ORD IDord-c97850dad1e640f3be7c1040606a58ea
Source noteuspto-grants-2006_10