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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246846Generated: October 30, 2026

D-Proline → HCID 21906766, compound

https://huagongshe.com/reaction/1246846

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ProlineHCID 8988—
Reactant4-HydroxypyrrolidineHCID 98210—
Reactant2-Chloro-4-(4-(2-methoxy-phenylsulfanyl)-3-trifluoromethyl-phenyl)-pyridineHCID 21906809—
ProductHCID 21906766HCID 21906766—

Reaction Steps

The title compound was prepared according to the procedures of Example 38E, substituting compound 76 with compound 96 (0.039 g, 0.0985 mmol) and 3-hydroxypyrrolidine with (D)-proline. A yellow solid 100 was obtained (0.0366 g, 78%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129247B2
Source datasetuspto-grants-2006_10
ORD IDord-616b2d5e68b34d4ebfc6e72b779b797b
Source noteuspto-grants-2006_10