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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247010Generated: October 31, 2026

Benzyl (S)-2-(7-methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylcarbamate → (S)-2-(7-Methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylamine

https://huagongshe.com/reaction/1247010

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl (S)-2-(7-methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylcarbamateHCID 86604076—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product(S)-2-(7-Methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylamineHCID 11988964—

Reaction Steps

To a solution of the product from Step E (60 mg, 0.157 mmol) in methanol (10 mL) was added 10% palladium-on-carbon (20 mg) and the mixture was stirred under an atmosphere of hydrogen at room temperature for 18 h. The reaction mixture was filtered and evaporated to a colorless oil (30 mg): LC/MS m/z 247.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129257B1
Source datasetuspto-grants-2006_10
ORD IDord-f32c1e8ecd9a49238595b28697e2b1d8
Source noteuspto-grants-2006_10