HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl (S)-2-(7-methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylcarbamate → (S)-2-(7-Methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl (S)-2-(7-methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylcarbamate | HCID 86604076 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (S)-2-(7-Methoxy-1H-pyrazolo[3,4-e]benzoxazol-1-yl)-1-methylethylamine | HCID 11988964 | — |
Reaction Steps
To a solution of the product from Step E (60 mg, 0.157 mmol) in methanol (10 mL) was added 10% palladium-on-carbon (20 mg) and the mixture was stirred under an atmosphere of hydrogen at room temperature for 18 h. The reaction mixture was filtered and evaporated to a colorless oil (30 mg): LC/MS m/z 247.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129257B1 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-f32c1e8ecd9a49238595b28697e2b1d8 |
| Source note | uspto-grants-2006_10 |