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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247237Generated: October 30, 2026

4-(Aminomethyl)benzonitrile → (RS)-2-(4-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamide

https://huagongshe.com/reaction/1247237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
Reactant2-[4-(Benzyloxy)phenyl]-2-methoxyacetic acidHCID 69290952—
Product(RS)-2-(4-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamideHCID 21904879—

Reaction Steps

(RS)-(4-Benzyloxy-phenyl)-methoxy-acetic acid was coupled with 4-aminomethyl benzonitrile to give (RS)-2-(4-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamide according to general procedure B. Colorless solid. MS 387.3 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-2fc3d717f3764ef1a39d35ccdac423c6
Source noteuspto-grants-2006_10