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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247242Generated: November 2, 2026

4-(Aminomethyl)benzonitrile → (RS)-2-(3-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamide

https://huagongshe.com/reaction/1247242

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
ReactantHCID 69289061HCID 69289061—
Product(RS)-2-(3-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamideHCID 21904929—

Reaction Steps

(RS)-(3-Benzyloxy-phenyl)-methoxy-acetic acid was coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-2-(3-benzyloxy-phenyl)-N-(4-cyano-benzyl)-2-methoxy-acetamide. Light yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-e7d6c98ce053485383908db8227808d9
Source noteuspto-grants-2006_10