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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247258Generated: November 1, 2026

2-[4-(Benzyloxy)phenyl]-2-methoxyacetic acid → 2-(4-Hydroxyphenyl)-2-methoxyacetic acid

https://huagongshe.com/reaction/1247258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(Benzyloxy)phenyl]-2-methoxyacetic acidHCID 69290952—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product2-(4-Hydroxyphenyl)-2-methoxyacetic acidHCID 18958975—

Reaction Steps

(RS)-(4-Benzyloxy-phenyl)-methoxy-acetic acid (example 3.1) was hydrogenated at rt and normal pressure using 10% Pd/C as a catalyst and EtOH as a solvent to give (RS)-(4-hydroxy-phenyl)-methoxy-acetic acid as a light grey solid. MS 181.4 ([M−H]−)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-33dd010defb9421e9cf4b3b3299ace92
Source noteuspto-grants-2006_10