反应详情

4-(1-Pyrrolidino)benzaldehyde was reacted according to general procedure A using methanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-methoxy-2-(4-pyrrolidin-1-yl-phenyl)-acetamide. Off-white solid. MS 350.4 ([M+H]+)