Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247291Generated: October 31, 2026

4-(Aminomethyl)benzonitrile → HCID 21905230, compound

https://huagongshe.com/reaction/1247291

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
Reactant4-(1H-imidazol-1-yl)benzaldehydeHCID 736530—
ReactantDioxane MethanolHCID 21966525—
ProductHCID 21905230HCID 21905230—

Reaction Steps

1-(4-Formylphenyl)-1H-imidazole was reacted according to general procedure A using methanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-(4-imidazol-1-yl-phenyl)-2-methoxy-acetamide. Colorless foam. MS 347.2 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-ff044ea5de3c41ee9a0c33ca00621fcf
Source noteuspto-grants-2006_10