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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247293Generated: October 30, 2026

4-(Aminomethyl)benzonitrile → HCID 21905112, compound

https://huagongshe.com/reaction/1247293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
Reactant4-MorpholinobenzaldehydeHCID 291349—
ReactantDioxane MethanolHCID 21966525—
ProductHCID 21905112HCID 21905112—

Reaction Steps

4-Morpholinobenzaldehyde was reacted according to general procedure A using methanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-methoxy-2-(4-morpholin-4-yl-phenyl)-acetamide. Orange oil. MS 366.2 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-7c5cf29ffd8d4365aa8f8e1c867571b5
Source noteuspto-grants-2006_10