反应详情

2-Fluoro-4-methoxybenzaldehyde was reacted according to general procedure A using n-propanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-propoxy-acetamide. Light yellow oil. MS 357.2 ([M+H]+)