HuagongsheHuagongshe Chemistry Print Report · For research reference only
(RS)-N-(4-cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-ethoxy-acetamide → (RS)-N-(4-Cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-methoxy-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (RS)-N-(4-cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-ethoxy-acetamide | HCID 21905759 | — |
| Reactant | (RS)-(2,6-difluoro-3-hydroxy-phenyl)-methoxy-acetic acid | HCID 69290134 | — |
| Product | (RS)-N-(4-Cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-methoxy-acetamide | HCID 21905078 | — |
Reaction Steps
(RS)-N-(4-Cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-methoxy-acetamide was prepared from (RS)-(2,6-difluoro-3-hydroxy-phenyl)-methoxy-acetic acid in analogy to (RS)-N-(4-cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-ethoxy-acetamide (example 213). White foam. MS 330.8 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-57cf153e1a1243ec997b5c5aea30c392 |
| Source note | uspto-grants-2006_10 |