Formic Acid → HCID 69290118, compound

Participants

Reaction Steps

A suspension of (S)-[(4-{[2-(2,6-difluoro-4-methoxy-phenyl)-2-methoxy-acetylamino]-methyl}-phenyl)-imino-methyl]-carbamic acid tert-butyl ester in water was treated with formic acid. The solution was stirred for 8 hrs at rt, then concentrated, redissolved twice in water, concentrated and dried to give (S)-N-(4-carbamimidoyl-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-methoxy-acetamide formiate (78 mg) as white foam. MS 364.1 ([M+H]+)

Provenance & Evidence