Benzoic acid, 2-iodo-, methyl ester → HCID 21907643, compound

HRID 1247495Notes

Reaction equation

HRID 1247495 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[CH:12]([C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:15]=1B(O)O)=[O:13]>>[CH:12]([C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:15]=1[C:2]1[CH:11]=[CH:10][CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5])=[O:13]

Participants

3

Reactant 2

HCID 69132Benzoic acid, 2-iodo-, methyl esterHCID 27343652-Formyl-4-methoxybenzeneboronic acid

Product 1

HCID 21907643HCID 21907643, compound

Procedure

Methyl 2-iodobenzoate was coupled to 2-formyl-4-methoxyphenylboronic acid using the procedure described in Example 4, Part A to provide methyl 2-(2′-formyl-4′-methoxyphenyl)benzoate. 1HNMR (300 MHz, CDCl3) δ 9.74 (s, 1H); 8.02 (d, 1H, J=7.7 Hz); 7.57 (t, 1H J=7.7 Hz); 7.50 (m, 2H); 7.28, 1, m); 7.17 (s, 2H); 3.91 (s, 3H); 3.64 (s, 3H).

Sources & evidence

ORD record
ord-7e3df3f8267f4e389575a09429a5b5f0
Source dataset
uspto-grants-2006_10
Patent number
US07129264B2

Reaction notes

Loading…