Sodium Hydroxide → HCID 11756838, compound

Participants

Reaction Conditions

Reaction Steps

{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-2-methyl-phenoxy}-acetic acid methyl ester (1.9 g, 3.5 mmol) was dissolved in warm ethanol (100 ml). 1N NaOH (7 ml, 7 mmol) was added and the reaction mixture was stirred for 2 h at 60° C. after which it was evaporated. The residue was treated with water (50 ml) and 1N HCl (8 ml) and extracted with dichloromethane (2×250 ml). The combined organic phases were dried and evaporated to give the title compound in 1.8 g (99%) yield.

Provenance & Evidence