HCID 68575962, compound → HCID 9980047, compound

Participants

Reaction Steps

A solution of {4-[3,3-bis-(4-chloro-phenyl)-allyloxy]-phenoxy}-acetic acid ethyl ester (140 mg, 0.3 mmol) in 1N NaOH (1 ml) and ethanol (10 ml) was stirred at room temperature for 18 hours. The reaxtion mixture was evaporated and the residue dissolved in water (5 ml) and 1 N HCl (1.2 ml). The aquous phase was extracted with ethyl acetate (3×15 ml), dried (MgSO4) and evaporated to give the title compound in 130 mg (99%) yield.

Provenance & Evidence