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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247902Generated: November 1, 2026

5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone → HCID 178423876, compound

https://huagongshe.com/reaction/1247902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidoneHCID 12783831—
Reactant2-[4-(2-Aminoethylsulfanylmethyl)-1,3-thiazol-2-yl]guanidineHCID 178512723—
SolventPyridineHCID 1049—
ProductHCID 178423876HCID 178423876—

Reaction Steps

2-(2-Guanidino-4-thiazolylmethylthio)ethylamine is heated under reflux in pyridine for 12 hours with 1.5 molar equivalents of 2-nitroamino-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone to give 2-[2-(2-guanidino-4-thiazolylmethylthio)ethylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04521418
Source datasetuspto-grants-1985_06
ORD IDord-ae06d64f3d48455b98cb95fc4c051d2d
Source noteuspto-grants-1985_06