HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → 1-(Pyridin-3-yl)-3-(pyrrolidin-1-yl)but-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | 1-(Pyridin-3-yl)butane-1,3-dione | HCID 300160 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-(Pyridin-3-yl)-3-(pyrrolidin-1-yl)but-2-en-1-one | HCID 53893504 | 38.7% |
Reaction Steps
To a solution of 16.32 g of 1-(3-pyridinyl)butan-1,3-dione in 200 ml of ethyl acetate was added 7.11 g of pyrrolidone. The mixture was stirred at room temperature and then the crystals were collected giving 7.0 g of 3-(1-pyrrolidinyl)-1-(3-pyridinyl)-2-buten-1-one, mp 116°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04521422 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-5e193af20ea64eeea285cec6476267df |
| Source note | uspto-grants-1985_06 |