HRID1247952

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12025

2-Pyrrolidinone

C4H7NO

HCID300160

Nicotinoylacetone

C9H9NO2

PRODUCTS

产物

HCID53893504

1-(Pyridin-3-yl)-3-(pyrrolidin-1-yl)but-2-en-1-one

C13H16N2O

收率 38.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

To a solution of 16.32 g of 1-(3-pyridinyl)butan-1,3-dione in 200 ml of ethyl acetate was added 7.11 g of pyrrolidone. The mixture was stirred at room temperature and then the crystals were collected giving 7.0 g of 3-(1-pyrrolidinyl)-1-(3-pyridinyl)-2-buten-1-one, mp 116°-118° C.

WORKUP

后处理

customthe crystals were collected