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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 124799Generated: November 4, 2026

Hydrochloric Acid → 5-chloro-N2-(2-fluoro-4-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

https://huagongshe.com/reaction/124799

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantIsopropanolHCID 3776—
Reactant2,5-Dichloro-N-(5-methyl-1H-pyrazol-3-yl)-4-pyrimidinamineHCID 11402272—
Reactant2-Fluoro-4-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)anilineHCID 67155568—
Product5-chloro-N2-(2-fluoro-4-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamineHCID 67155312—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-bf701928c5744f208b703adc1e346abc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)