HCID 70489765, compound → HCID 13472332, compound

Participants

Reaction Steps

N-(1-Indanyl)alanine ethyl ester hydrochloride (9.0 g) is dissolved in 100 ml of 5N hydrochloric acid, and the mixture is refluxed for 3 hours. The reaction mixture is concentrated to dryness under reduced pressure, 10 ml of water is added to the residue, and the mixture is neutralized with aqueous ammonia. The resulting crystalline precipitates are collected by filtration, washed with water, and dried, to give 5.8 g of N-(1-indanyl)alanine as colorless scales. Melting point: 248°-250° C.

Provenance & Evidence