Water → 3-(Cyclohexylmethyl)heptanoic acid

HRID 1248196Notes

Reaction equation

HRID 1248196 reaction equation
[CH:1]1([CH2:7][CH:8]([CH2:12][CH2:13][CH2:14][CH3:15])[CH2:9][C:10]#N)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH2:16].S(=O)(=O)(O)[OH:18]>>[CH:1]1([CH2:7][CH:8]([CH2:12][CH2:13][CH2:14][CH3:15])[CH2:9][C:10]([OH:18])=[O:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 202790613-(Cyclohexylmethyl)heptanenitrile

Product 1

HCID 202790563-(Cyclohexylmethyl)heptanoic acid

Procedure

3-(Cyclohexylmethyl)heptanenitrile (1.43 g) in 10 ml of 50% aqueous sulfuric acid was heated under reflux overnight. The cooled mixture was then poured into water (100 ml) and extracted twice with ether. The ethereal extracts were washed with water, dried (MgSO4) and evaporated to give 3-(cyclohexylmethyl)heptanoic acid.

Workup

  1. temperatureunder reflux overnight
  2. extractionextracted twice with ether
  3. washThe ethereal extracts were washed with water
  4. dry with materialdried (MgSO4)
  5. customevaporated

Sources & evidence

ORD record
ord-186a570d2f634d30a9148c3d2213196f
Source dataset
uspto-grants-1985_06
Patent number
US04522948

Reaction notes

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