Ethyl chloroformate → HCID 20278951, compound

Participants

Reaction Steps

To a stirred mixture of 15 parts of [1-(phenylmethyl)-4-piperidinyl](2-thienyl)methanone in 120 parts of benzene are added dropwise 8 parts of ethyl carbonochloridate. Upon completion, the whole is heated to reflux and stirred for 6 hours at reflux temperature. The reaction mixture is cooled, filtered and evaporated, yielding 13 parts of ethyl 4-(2-thienylcarbonyl)-1-piperidinecarboxylate as a residue.

Provenance & Evidence