Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 1-Hexylpiperazine | HCID 2736513 | — |
| Reactant | 1-Chlorohexan-3-one | HCID 13458588 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 13458590 | HCID 13458590 | — |
Reaction Steps
A mixture of 15.3 g (0.09 mole) of n-hexyl piperazine and 12.3 g (0.091 mole) of 1-chloro-3-hexanone was heated to 100° C. for 5 minutes, cooled and dissolved in isopropanol. Isopropanolic HCl was added until acidic. Ether was added and the salt was filtered off. The product was crystallized from acetonitrile to yield 16.5 g of product with a melting point of 225°-230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04523014 |
|---|
| Source dataset | uspto-grants-1985_06 |
|---|
| ORD ID | ord-e035aef679dd4842b25164072c059a59 |
|---|
| Source note | uspto-grants-1985_06 |
|---|
