4-Cyanobenzoyl chloride → HCID 54275773, compound

HRID 1248346Notes

Reaction equation

HRID 1248346 reaction equation
[Cl-].[Cl-].[Cl-].[Al+3].[CH3:5][O:6][C:7]([C:9]1[C:12]2[CH:13]=[C:14]([O:17]C)[CH:15]=[CH:16][C:11]=2[CH:10]=1)=[O:8].[C:19]([C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1)#[N:20]>>[CH3:5][O:6][C:7]([C:9]1[C:12]2[CH:13]=[C:14]([OH:17])[C:15]([C:25](=[O:26])[C:24]3[CH:28]=[CH:29][C:21]([C:19]#[N:20])=[CH:22][CH:23]=3)=[CH:16][C:11]=2[CH:10]=1)=[O:8]

Participants

4

Reactant 3

HCID 801724-Cyanobenzoyl chlorideHCID 6451240Aluminum(III) ChlorideHCID 541184135-Methoxybenzocyclobutene-1-carboxylic acid methyl ester

Product 1

HCID 54275773HCID 54275773, compound

Procedure

In a manner analogous to that described in Example 5, starting from 26.6 g of aluminium trichloride, 9.61 g of 5-methoxybenzocyclobutene-1-carboxylic acid methyl ester and 17.56 g of p-cyanobenzoyl chloride there is obtained 4-(p-cyanobenzoyl)-5-hydroxybenzocyclobutene-1-carboxylic acid methyl ester having a melting point of 113°-114°.

Sources & evidence

ORD record
ord-432aa8a93fb4461bba9383b98ce36a57
Source dataset
uspto-grants-1985_06
Patent number
US04523030

Reaction notes

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