Acetic Acid → HCID 20279418, compound

Participants

Reaction Steps

2 g of 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carboxamide in 20 ml of acetic acid and 20 ml of concentrated hydrochloric acid are stirred for 4 hours at 95°-100°. The mixture is left to cool, filtered with suction, washed with water and recrystallised from trichloromethane/hexane. 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carboxylic acid is obtained having a melting point of 202°-203°.

Provenance & Evidence