Dimethylformamide → HCID 53714737, compound

Participants

Reaction Steps

3.37 g of 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carboxylic acid are suspended in 100 ml of toluene; 0.1 ml of dimethylformamide and 1.64 g of thionyl chloride are added and the whole is heated to 80°, stirred for 2 hours at 80°-90° and concentrated to dryness by evaporation under reduced pressure. 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carboxylic acid chloride is obtained which can be used without being further treated.

Provenance & Evidence