反应详情

A suspension of 20 g of 1-[3'-(2"-chloro-4"-trifluoromethylphenylthio)-phenyl]-4,5-dichloropyridaz-6-one, 5.3 g of sodium methylate and 0.1 g of N-methylpyrrolidone in 150 ml of absolute toluene was kept at 60° C. for 2 hours, while stirring. The solution formed was diluted with 200 ml of ether, treated with twice 100 ml of water, dried, filtered and evaporated down under reduced pressure. The oily residue was triturated with diisopropyl ether, and the product was filtered off under suction. 15.7 g (80% of theory) of 1-[3'-(2"-chloro-4"-trifluoromethylphenylthio)-phenyl]-4,5-dimethoxypyridaz-6-one of melting point 86° to 90° C. were obtained.

1. customThe solution formed
2. customdried
3. filtrationfiltered
4. customevaporated down under reduced pressure
5. customThe oily residue was triturated with diisopropyl ether
6. filtrationthe product was filtered off under suction