Ammonia → 4-Cyclopropyl-6-(trichloromethyl)-1,3,5-triazin-2-amine

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Reaction Steps

71.2 g of 2-cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine are dissolved in 70 ml of tetrahydrofuran, and, with stirring, 300 ml of concentrated aqueous ammonia solution are added at room temperature. The mixture is stirred for 30 minutes; it is then diluted with water, and the formed emulsion is extracted with ether. The ether phases are collected, dried, filtered and subsequently concentrated by evaporation. The yield is 48 g of the crystalline title product, m.p. 111°-114° C.

Provenance & Evidence