Ammonia → HCID 20199615, compound

HRID 1248376Notes

Reaction equation

HRID 1248376 reaction equation
[CH:1]1([C:4]2[N:9]=[C:8]([C:10]([Cl:13])([Cl:12])[Cl:11])[N:7]=[C:6](C(Cl)(Cl)Cl)[N:5]=2)[CH2:3][CH2:2]1.[NH3:18]>O1CCCC1.O>[NH2:18][C:6]1[N:5]=[C:4]([CH:1]2[CH2:2][CH2:3]2)[N:9]=[C:8]([C:10]([Cl:13])([Cl:12])[Cl:11])[N:7]=1

Participants

5

Reactant 2

HCID 222AmmoniaHCID 201996132-Cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine

Product 1

HCID 20199615HCID 20199615, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

71.2 g of 2-cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine are dissolved in 70 ml of tetrahydrofuran, and, with stirring, 300 ml of concentrated aqueous ammonia solution are added at room temperature. The mixture is stirred for 30 minutes; it is then diluted with water, and the formed emulsion is extracted with ether. The ether phases are collected, dried, filtered and subsequently concentrated by evaporation. The yield is 48 g of the crystalline title product, m.p. 111°-114° C.

Workup

  1. stirringThe mixture is stirred for 30 minutes
  2. extractionthe formed emulsion is extracted with ether
  3. customThe ether phases are collected
  4. customdried
  5. filtrationfiltered
  6. concentrationsubsequently concentrated by evaporation

Sources & evidence

ORD record
ord-e9c2a3dea5cd4219aa7a28875b3b479f
Source dataset
uspto-grants-1985_06
Patent number
US04523947

Reaction notes

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