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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1248545Generated: October 26, 2026

2,6-Dichloroquinoxaline → Methyl 4-[4-(6-chloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoate

https://huagongshe.com/reaction/1248545

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DichloroquinoxalineHCID 87748—
ReactantMethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoateHCID 53786660—
ProductMethyl 4-[4-(6-chloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoateHCID 54426457—

Reaction Steps

The procedure of Example 37 is repeated using 2,6-dichloroquinoxaline and methyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate as the starting materials to yield methyl 4-[4-(6-chloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoate which is treated with 35% HClO4 to yield the 3-oxo ester. Methyl 4-[4-(6-chloro-2-quinoxalyloxy)phenoxy]-3-oxopentanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04525205
Source datasetuspto-grants-1985_06
ORD IDord-7b69b6ecdd034aeb99d41a02ef2c91e0
Source noteuspto-grants-1985_06