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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1248551Generated: November 3, 2026

Glycine → 2-[(Butan-2-yl)amino]acetic acid

https://huagongshe.com/reaction/1248551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantMethanolHCID 887—
ReactantMethyl Ethyl KetoneHCID 6569—
CatalystPalladiumHCID 23938—
SolventWaterHCID 962—
Product2-[(Butan-2-yl)amino]acetic acidHCID 42811—

Reaction Steps

338 g of glycine (4.5 mols), 1.5 liters of methanol, 15 g of 10% Pd on C, wet with water, and 500 g of methylethylketone (6.93 mols) are charged into the autoclave.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04525294
Source datasetuspto-grants-1985_06
ORD IDord-0e503d9cabf14a2ca3a5523662e552cc
Source noteuspto-grants-1985_06