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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 124862Generated: October 25, 2026

1,2-Dichloroethane → Tert-butyl 2-(cyclobutylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

https://huagongshe.com/reaction/124862

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantCyclobutylamineHCID 75645—
Reactant1-((Tert-butoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acidHCID 335255—
ProductTert-butyl 2-(cyclobutylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylateHCID 77197642—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-f145a56244e947138a75a2c743ccbdb4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)