1,2-Dichloroethane → Tert-butyl 2-(cyclobutylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[OH:16])[CH2:10][CH:11]([OH:13])[CH2:12]1.[CH2:22]([Cl:23])[CH2:24][Cl:25].[CH:17]1([NH2:21])[CH2:18][CH2:19][CH2:20]1.[Na+:30].[O-:26][C:27]([OH:28])=[O:29].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:16])[NH:21][CH:17]2[CH2:18][CH2:19][CH2:20]2)[CH2:10][CH:11]([OH:13])[CH2:12]1Participants
7
Sources & evidence
- ORD record
- ord-f145a56244e947138a75a2c743ccbdb4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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