HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → ethyl N-cyclohexyl-N-[2-[cyclohexyl(ethoxycarbonyl)amino]ethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N,N'-Dicyclohexyl-1,2-ethanediamine | HCID 273886 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | ethyl N-cyclohexyl-N-[2-[cyclohexyl(ethoxycarbonyl)amino]ethyl]carbamate | HCID 332259 | — |
Reaction Steps
The N,N'-dicyclohexyl-N,N'-bis(ethoxycarbonyl)-ethylenediamine (m.p. 108° C.) is prepared by reacting N,N'-dicyclohexylethylenediamine with ethyl chlorocarbonate in chloroform at 10°-20° C. in the presence of aqueous NaOH. The obtained product has a purity of 99.7% and is used directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04525503 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-138224ee8a414990ab6a30b9ff858b1e |
| Source note | uspto-grants-1985_06 |