Hydrogen Peroxide → HCID 178449941, compound

HRID 1248777Notes

Reaction equation

HRID 1248777 reaction equation
[Cl:1][CH:2]=[CH:3][CH2:4][O:5][N:6]=[C:7]([C@H:11]1[C:16](=[O:17])[CH2:15][C@H:14]([CH2:18][CH:19]([S:21][CH2:22][CH3:23])[CH3:20])[CH2:13][C:12]1=[O:24])[CH2:8][CH2:9][CH3:10].[OH:25]O>CC(C)=O>[Cl:1][CH:2]=[CH:3][CH2:4][O:5][N:6]=[C:7]([C@H:11]1[C:12](=[O:24])[CH2:13][C@H:14]([CH2:18][CH:19]([S:21]([CH2:22][CH3:23])=[O:25])[CH3:20])[CH2:15][C:16]1=[O:17])[CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 178449940HCID 178449940, compound

Product 1

HCID 178449941HCID 178449941, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In this example, a mixture containing 2.2 g of trans-2-[1-(3-chloroallyloxyimino)butyl]-5-(2-ethylthiopropyl) cyclohexane 1,3-dione and 1 ml of aqueous 30% hydrogen peroxide in 10 ml of acetone was stirred at room temperature for about 21/2 days and then concentrated by evaporation. The residue was mixed with 50 ml of ethyl ether, washed with 30 ml of saturated aqueous sodium bicarbonate solution, then washed with 30 ml of water, dried over magnesium sulfate and evaporated to dryness affording 1.9 g of the title compound.

Workup

  1. concentrationconcentrated by evaporation
  2. additionThe residue was mixed with 50 ml of ethyl ether
  3. washwashed with 30 ml of saturated aqueous sodium bicarbonate solution
  4. washwashed with 30 ml of water
  5. dry with materialdried over magnesium sulfate
  6. customevaporated to dryness

Sources & evidence

ORD record
ord-ee6d8f7ca833453bb316d7c0fb4ab716
Source dataset
uspto-grants-1986_12
Patent number
US04626276

Reaction notes

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