3'-Aminoacetophenone → HCID 898301, compound

HRID 1248808Notes

Reaction equation

HRID 1248808 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8](=[O:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[CH:11]1([C:15](Cl)=[O:16])[CH2:14][CH2:13][CH2:12]1.C(N(C(C)C)CC)(C)C>ClCCl>[C:8]([C:4]1[CH:3]=[C:2]([NH:1][C:15]([CH:11]2[CH2:14][CH2:13][CH2:12]2)=[O:16])[CH:7]=[CH:6][CH:5]=1)(=[O:10])[CH3:9]

Participants

5

Reactant 3

HCID 74173'-AminoacetophenoneHCID 78705Cyclobutanecarbonyl chlorideHCID 81531Diisopropylethylamine

Product 1

HCID 898301HCID 898301, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

m-Aminoacetophenone, cyclobutanecarboxylic acid, chloride and diisopropylethylamine in dichloromethane were reacted, giving N-(3-acetylphenyl)cyclobutanecarboxamide.

Sources & evidence

ORD record
ord-4ec364baffce4ce898ad014d2782f596
Source dataset
uspto-grants-1986_12
Patent number
US04626538

Reaction notes

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