1-Propanol → HCID 20226080, compound

HRID 1248818Notes

Reaction equation

HRID 1248818 reaction equation
[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:20]([OH:23])[CH2:21][CH3:22]>>[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH:14]([CH:20]([OH:23])[CH2:21][CH3:22])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 10311-PropanolHCID 20226075HCID 20226075, compound

Product 1

HCID 20226080HCID 20226080, compound

Procedure

1.0 g (3.5 mMol) of product from Example 28 were reacted with 0.76 ml (~10 mMol) of propanol for 5 days in the manner described in Example 29 and the separated into the erythro and threo forms by chromatography on silica gel using toluene/ethyl acetate 4:1.

Workup

  1. customthe separated into the erythro and threo forms by chromatography on silica gel

Sources & evidence

ORD record
ord-8a91322030464c8b83420f4cbb480c49
Source dataset
uspto-grants-1986_12
Patent number
US04626535

Reaction notes

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