Pentanal → HCID 20226081, compound

HRID 1248820Notes

Reaction equation

HRID 1248820 reaction equation
[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:20](=[O:25])[CH2:21][CH2:22][CH2:23][CH3:24]>C(OCC)(=O)C>[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:20]([OH:25])[CH2:21][CH2:22][CH2:23][CH3:24])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 8063PentanalHCID 20226075HCID 20226075, compound

Product 1

HCID 20226081HCID 20226081, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

1.0 g (3.5 mMol) of product from Example 28 were reacted with 1.1 g (~10 mMol) of n-pentanal for 9 days in the manner described in Example 29 and, after aqueous work-up, the product was isolated from the ethyl acetate extract. A 1:1 mixture of the erythro and threo forms resulted.

Workup

  1. extractionextract
  2. additionA 1:1 mixture of the erythro and threo forms
  3. customresulted

Sources & evidence

ORD record
ord-7dcfd627a53b4989aea1c91a71a0bd39
Source dataset
uspto-grants-1986_12
Patent number
US04626535

Reaction notes

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