Methanesulfonic Acid → HCID 13588230, compound

HRID 1248831Notes

Reaction equation

HRID 1248831 reaction equation
[Cl:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[C:11]([O:17]CC4C=CC=CC=4)[CH:12]=3)[NH:7][C:6]=2[C:5]([N+:25]([O-:27])=[O:26])=[CH:4][CH:3]=1.CS(O)(=O)=O>C(O)(=O)C>[Cl:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[C:11]([OH:17])[CH:12]=3)[NH:7][C:6]=2[C:5]([N+:25]([O-:27])=[O:26])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 135883221-Chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Product 1

HCID 13588230HCID 13588230, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a stirred and boiling mixture of 26.7 g of 1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone in 1.9 l of glacial acetic acid was added 13.0 ml of methanesulfonic acid. Heating and stirring were continued for seven hours and the mixture was filtered. The precipitate was suspended in 250 ml of boiling glacial acetic acid, cooled to 60°, collected, washed with water and then methanol, and dried providing the title compound, mp above 325° C.

Workup

  1. temperatureHeating
  2. stirringstirring
  3. filtrationthe mixture was filtered
  4. temperaturecooled to 60°
  5. customcollected
  6. washwashed with water
  7. dry with materialmethanol, and dried

Sources & evidence

ORD record
ord-706d21d94aac4a13903d4d70fe288ebf
Source dataset
uspto-grants-1986_12
Patent number
US04626540

Reaction notes

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