反应详情

30.4 g of 3,4-diaminobenzoic acid, 50 g of carbon disulfide and 50 g of triethylamine were dissolved in 200 ml of dioxane and the solution was refluxed by heating for 5 hours. The reaction mixture was cooled to room temperature, the crystals thus deposited were collected by filtration and recrystallized from water to obtain 14 g of 2-mercapto-5-carboxybenzimidazole. Melting Point: above 250° C.

1. temperaturethe solution was refluxed
2. temperatureby heating for 5 hours
3. filtrationthe crystals thus deposited were collected by filtration
4. customrecrystallized from water