Dichloromethane → tert-butyl N-[2-[3-[4-[1-(4-bromoanilino)-4-[tert-butyl(dimethyl)silyl]oxy-1-oxobutan-2-yl]phenyl]prop-2-enoylamino]phenyl]carbamate
Reaction equation
[Br:61][c:62]1[cH:63][cH:64][c:65]([NH2:68])[cH:66][cH:67]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[c:10]([NH:15][C:16](=[O:17])[CH:18]=[CH:19][c:20]2[cH:21][cH:22][c:23]([CH:26]([C:27](=[O:28])[OH:29])[CH2:30][CH2:31][O:32][Si:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[CH3:39])[cH:24][cH:25]2)[cH:11][cH:12][cH:13][cH:14]1.[CH3:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH2:46][CH2:47][N:48]([CH3:49])[CH3:50].[Cl:69][CH2:70][Cl:71].[OH:51][n:52]1[c:53]2[c:54]([cH:55][cH:56][cH:57][cH:58]2)[n:59][n:60]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[c:10]([NH:15][C:16](=[O:17])[CH:18]=[CH:19][c:20]2[cH:21][cH:22][c:23]([CH:26]([C:27](=[O:28])[NH:68][c:65]3[cH:64][cH:63][c:62]([Br:61])[cH:67][cH:66]3)[CH2:30][CH2:31][O:32][Si:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[CH3:39])[cH:24][cH:25]2)[cH:11][cH:12][cH:13][cH:14]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-69260a84eb684b039a38836d93461e6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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