HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl [[[4-(hydroxymethyl)-6-methylpyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 13769577 | HCID 13769577 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Methyl [[[4-(hydroxymethyl)-6-methylpyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate | HCID 13769578 | 81.4% |
Reaction Steps
A solution of 6 g of the product prepared in Example 4 in 50 ml of acetone was stirred with 3 ml of 1N aqueous HCl for 3 days at room temperature, concentrated at reduced pressure, and the residue was thoroughly washed with water to provide 4 g of the title compound, m.p. 140°-141°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04629494 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-872a8e88307b4a3aa0fe6b3b4eb493a6 |
| Source note | uspto-grants-1986_12 |