Hydrochloric Acid → HCID 13769578, compound

HRID 1249120Notes

Reaction equation

HRID 1249120 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][O:9]C2CCCCO2)[N:5]=[C:4]([NH:16][C:17]([NH:19][S:20]([C:23]2[CH:32]=[CH:31][CH:30]=[CH:29][C:24]=2[C:25]([O:27][CH3:28])=[O:26])(=[O:22])=[O:21])=[O:18])[N:3]=1.Cl>CC(C)=O>[OH:9][CH2:8][C:6]1[CH:7]=[C:2]([CH3:1])[N:3]=[C:4]([NH:16][C:17]([NH:19][S:20]([C:23]2[CH:32]=[CH:31][CH:30]=[CH:29][C:24]=2[C:25]([O:27][CH3:28])=[O:26])(=[O:22])=[O:21])=[O:18])[N:5]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13769577HCID 13769577, compound

Product 1

HCID 13769578HCID 13769578, compoundYield 81.4%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 6 g of the product prepared in Example 4 in 50 ml of acetone was stirred with 3 ml of 1N aqueous HCl for 3 days at room temperature, concentrated at reduced pressure, and the residue was thoroughly washed with water to provide 4 g of the title compound, m.p. 140°-141°.

Workup

  1. concentrationconcentrated at reduced pressure
  2. washthe residue was thoroughly washed with water

Sources & evidence

ORD record
ord-872a8e88307b4a3aa0fe6b3b4eb493a6
Source dataset
uspto-grants-1986_12
Patent number
US04629494

Reaction notes

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