HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Aminopyridine → 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Aminopyridine | HCID 1727 | — |
| Edukt | 1,3-Dichloro-2-isocyanatobenzene | HCID 604537 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea | HCID 4610560 | — |
Reaktionsschritte
A solution of 4.7 g (0.05 mole) of 4-aminopyridine in 300 ml of anhydrous tetrahydrofuran was treated with 9.4 g (0.05 mole) of 2,6-dichlorophenylisocyanate. The solution was heated at reflux for 24 hours, cooled, and concentrated in vacuo to a solid. Recrystallization from aqueous ethanol afforded the crystalline product, mp 217°-219° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04629731 |
| Quelldatensatz | uspto-grants-1986_12 |
| ORD ID | ord-36544aebbdc84efa9491c1941afa03f0 |
| Quellennotiz | uspto-grants-1986_12 |