HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(4-Hydroxyanilino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chlorobenzoic Acid | HCID 8374 | — |
| Reactant | 4-Benzyloxyaniline | HCID 22860 | — |
| Reactant | HCID 13749492 | HCID 13749492 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(4-Hydroxyanilino)benzoic acid | HCID 11593806 | — |
Reaction Steps
The corresponding free acid, 2-(4-hydroxyphenylamino)benzoic acid, yellow solid m.p. 233° C.(decompn.) was prepared by hydrogenation of 5 g of 2-(4-benzyloxyphenylamino)benzoic acid in 250 ml of ethanol containing 2 ml of concentrated hydrochloric acid and 2 g of palladium-on-carbon catalyst. The benzyloxy compound was in turn prepared by reaction of 2-chlorobenzoic acid and 4-benzyloxyaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04629735 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-36fd7fb1d915456bb894590af75f5d44 |
| Source note | uspto-grants-1986_12 |