HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetonitrile → 2-[Ethyl(heptyl)amino]acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetonitrile | HCID 7856 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Heptanamine, N-ethyl- | HCID 48038 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-[Ethyl(heptyl)amino]acetonitrile | HCID 20225324 | — |
Reaction Conditions
| Temperature | 125 °C |
|---|
Reaction Steps
Combine 7.95 g (0.055 moles) ethyl(heptyl)amine, 3.5 ml (0.055 moles) chloroacetonitrile, 5.8 g (0.055 moles) sodium carbonate and 25 ml toluene in a sealed pressure tube. Heat to 125° C. for 18 hrs. Follow the progress of the reaction by thin layer chromatography on silica gel (CH3CN+MeOH+NH4OH, 85+10+5). At the completion of the reaction, filter the reaction mixture and evaporate the solvents to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04629739 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-cd3f4c535923482a92d0056b5625a353 |
| Source note | uspto-grants-1986_12 |