Methoxymethyl-triphenylphosphonium chloride → HCID 178444484, compound

HRID 1249308Notes

Reaction equation

HRID 1249308 reaction equation
[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH:12]=O)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].[Cl-].[CH3:15][O:16]C[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>O1CCCC1>[CH2:1]([C@H:6]1[CH2:7][CH2:8][C@H:9]([CH2:12][CH:15]=[O:16])[CH2:10][CH2:11]1)[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 2723798Methoxymethyl-triphenylphosphonium chlorideHCID 178444538HCID 178444538, compound

Product 1

HCID 178444484HCID 178444484, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a manner analogous to that described in Example 2, paragraphs (a) and (b), trans-4-pentylcyclohexanecarboxaldehyde was reacted in a Wittig reaction with methoxymethyl-triphenylphosphonium chloride and potassium t-butylate and the resulting enol ether was subsequently hydrolyzed in tetrahydrofuran/2N hydrochloric acid to give (trans-4-pentylcyclohexyl)acetaldehyde.

Sources & evidence

ORD record
ord-8ccbb91307b545b69bccb48e8ca5532c
Source dataset
uspto-grants-1986_12
Patent number
US04630896

Reaction notes

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