Phenylhydrazine → ST50547281

HRID 1249340Notes

Reaction equation

HRID 1249340 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9][N:10]=[C:11]=[S:12]>C1C=CC=CC=1>[CH3:9][NH:10][C:11](=[S:12])[NH:8][NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 7516PhenylhydrazineHCID 11167Methyl isothiocyanate

Product 1

HCID 4405145ST50547281Yield 67.4%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

108 g of phenylhydrazine was dissolved in 500 ml of benzene and thereto 73 g of methylisothiocyanate was added dropwise. The reaction mixture was heated and refluxed. As the reaction proceeded, crystals separated out. These were filtered off and dried. Thus, 122 g of 4-methyl-1-phenylthiosemicarbazide was obtained.

Workup

  1. temperatureThe reaction mixture was heated
  2. temperaturerefluxed
  3. customcrystals separated out
  4. filtrationThese were filtered off
  5. customdried

Sources & evidence

ORD record
ord-c6b0771645654007bf186579b7473edf
Source dataset
uspto-grants-1986_12
Patent number
US04631253

Reaction notes

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