HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → HCID 13603437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | HCID 13603435 | HCID 13603435 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13603437 | HCID 13603437 | 61.2% |
Reaction Steps
30.0 g of 4-(2,3-epoxypropoxy)-phenylacetone and 25.6 g of 2-methoxyphenyl-piperazine are heated under reflux in 300 ml of ethanol for 3 hours. The solvent is then distilled off. The residue is made to crystallise with ethyl acetate/hexane. 32.5 g of 1-[4-(propan-2-on-yl)-phenoxy]-3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propan-2-ol are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04631281 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-36bef0fc4f964df5972aedad41b67e5e |
| Source note | uspto-grants-1986_12 |